Watch: Will Smith in Trailer for Movie About Concussions in the NFL  

Will Smith is tackling concussions in his upcoming film, Concussion, about Dr. Bennet Omalu, the famed doctor who discovered neurodegenerative disease, which many NFL players have suffered after repeated head trauma.

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Omalu’s research on the brains of ex-NFL players Dave Duerson and Andre Waters led him to realize that symptoms of chronic traumatic encephalopathy are memory loss and depression. Duerson and Waters both committed suicide after suffering from the disease.

In the movie, Smith’s character goes toe-to-toe with the NFL in his battle to get the organization to understand the importance of his research and how it affects the league’s players.

Watch the riveting trailer below:

Concussion is set to be released in cinemas on Dec. 25.